Dementia
Dementia:
General Information
|
When?
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Time 1
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Time 2
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Time 3
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Time 4
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Time 5
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Time 6
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Time 7
|
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Where?
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Intake Assessment
(EE)
Intensive Protocol
(IP)
|
Intake Assessment
(EE)
|
Intake Assessment
(EE)
Intensive Protocol
(IP)
|
Intake Assessment
(EE)
Intensive Protocol
(IP)
|
Intake Assessment
(EE)
|
Intake Assessment
(EE)
|
Intake Assessment
(EE)
|
|
Questionnaire
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EE:
a) Short Mini Mental State (SMMS)
pp. 13-15
IP:
1. Neuropsychological Testing: Manual
a) Enhanced Cued Recall (ECR)
Trial 1-3
pp. 1-4
b) Complex Figures Reconstruction (KF
p. 4
c) Complex Figure Copy Task
p. 6
d) Reitan Trail Making (RTM)
p. 5
Neuropsychological Testing: Test
sheets
e) Mini Mental State Examination (MMSE)
pp. 10-17
f) Unusual questions
p. 18
2. Psychopathology
a) Specific Behavior and Speech scale
|
EE:
a) Short Mini Mental State (SMMS)
pp. 18-20
|
EE:
a) Short Mini Mental State (SMMS)
pp.18-19
IP:
1. Neuropsychological Testing
a) Enhanced Cued Recall (ECR)
Trial 1-2
b) Mini Mental State Examination (MMSE)
2. Psychopathology
a) Specific Behavior and Speech scale
|
EE:
a) Short Mini Mental State (SMMS)
pp. 18-19
IP:
1. Neuropsychological Testing
a) Enhanced Cued Recall (ECR)
Trial 1-2
b) Mini Mental State Examination (MMSE)
2. Psychopathology
a) Specific Behavior and Speech scale
|
EE:
1. Neuropsychological Testing
a) Enhanced Cued Recall (ECR)
Trial
b) Mini Mental State Examination (MMSE)
|
EE:
a) Mini Mental State (MMS)
pp. 26-30
b) Enhanced Cued Recall (ECR)
p. 30
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EE:
a) Mini Mental State (MMS)
pp. 28-32
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SIR Data bank
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EE:
Psycha
rec/table 20 (q1neuro3)
IP:
1.Neuropsychologiscal Testing
a) Psycha
rec/table 18 (q1neuro1)
rec/table 19 (q1neuro2)
b) Psycha
rec/table 20 (q1neuro3)
c) Psycha
rec/table 20 (q1neuro3)
d) Psycha
rec/table 20 (q1neuro3)
e)Psycha
rec/table 20 (q1neuro3)
2.Psychopathology
Psycha rec/table 11 (q1psypat)
|
EE:
Psycha
rec/table 120 (q2neuro3)
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EE:
Psycha
rec/table 220 (q3neuro3)
IP:
1. Neuropsychological Testing
a) Psycha
rec/table 218 (q3neuro1)
b) Psycha
rec/table 220 (q3neuro3)
2. Psychopathology
Psycha
rec/table 211 (q3psypat)
|
EE:
Psycha
rec/table 320 (q4neuro3)
IP:
1. Neuropsychological Testing
a) Psycha
rec/table 318 (q4neuro1)
b) Psycha
rec/table 320 (q3neuro3)
2. Psychopathology
Psycha
rec/table 311 (q4psypat)
|
EE:
ZPK
rec/table 410 (z5ee)
|
EE:
ZPK
rec/table 510 (z6ee)
|
EE:
ZPK
rec/table 610 (z7ee)
|
To assess a demential syndrome, several instruments were
used in BASE:
(1) For screening purposes, the short version of the Mini
Mental State (Short MMS, Klein et al., 1985; see Literature)
was used within the multidisciplinary intake assessment (EE).
(2) Within the intensive protocol (IP, neuropsychological
test-session), the Mini Mental State examination (Folstein,
1975; see Literature) was
used.
(3) A Dementia score was built from the dementia-related items
of Specific Behavior and Speech Scale (see Psychopathology)
which was part of the observation protocol. This scale
was used by the interviewers to rate whether the participant behaved
in an unusual manner.
(4) Additionally, relatives were asked questions related to demential
symptoms (Angehörigen-Interview).
(5) Further, the degree of dementia was assessed by (a) the
MMS result, (b) the Clinical Dementia Rating scheme (CDR; Hughes et
al., 1982; see Literature)
and (c) a semi-structured interview conducted with the participant's
family doctor (see Physician
Interview: Items 49 - 57).
Disorders in cognitive performance were measured as follows:
Memory disorders were assessed by (a) the repetition,
recognition, and incidental learning tasks of the Enhanced Cued
Recall, 16 items each, (ECR; Grober et al. 1988; see Literature),
which is used to detect disorders in memory and speech; and (b) the
Complex Figures Reconstruction (KF; Osterrieth, 1944,
Read, 1987; see Literature).
The KF test detects disorders in memory and constructive apraxia.
Speech disorders were assessed (a) by the naming and pointing
tasks of the Enhanced Cued Recall, 16 concrete items each
(ECR, Grober et al. 1988; see Literature).
Constructive apraxia was assessed by the Complex Figure
Copy task.
Psychomotor slowing was assessed by the Reitan Trail
Making test (RTM; Reitan, 1958; see Literature).
Literature: Helmchen,
Baltes, Geiselmann, Kanowski, Linden, Reischies, Wagner, & Wilms,
1996; Reischies & Lindenberger, 1996; Helmchen, Baltes,
Geiselmann, Kanowski, Linden, Reischies, Wagner, Wernicke, &
Wilms, 1999.
Dementia:
Instruments / Items used in BASE
Note:
According to the design, EE variable names for Time 1 have
the prefix z1, names for Time 2 have the prefix z2,
names for Times 3 have the prefix z3, and names for Time 4 have the
prefix z4.
IP variable names for Time 1 have the prefix q1, names for
Time 3 have the prefix q3, names for Time 4 have the prefix q4.
Variables for Time 5, Time 6, and Time 7 have
been administered in the EE, but are displayed below according
to the task performed.
Variable names for Time 5 have the prefix z5, names for Time 6 have
the prefix z6,
and names for Times 7 have the prefix z7.
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Task
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Variable names
Time 1
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Variable names
Time 2
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Variable names
Time 3
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Variable names
Time 4
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Variable names
Time 5
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Variable names
Time 6
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Variable names
Time 7
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EE (Intake assessment)
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Short MMS
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1. a-c
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short term memory (1.)
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z1e56x1/x2 /x3
Apfel/Tisch/
Pfennig
|
+
Butter/Uhr/
Nagel
|
+
Auto/Blume/
Kerze
|
+
Auto/Blume/
Kerze
|
-
|
-
|
-
|
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2. a-d
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current date / month / year / day of the week
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z1e57
/58 /59 /60
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+
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+
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+
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-
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-
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-
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3. a-e
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1. / 2. / 3. / 4. / 5. substraction
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z1e61x1
/x2 /x3 /x4 /x5
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+
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+
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+
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-
|
-
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-
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4. a-e
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backwards spelling
(V / O / G / E / L)
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z1e62x1
/x2 /x3 /x4 /x5
|
+
|
+
|
+
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-
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-
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-
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|
5. a-c
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short term memory (2.)
|
z1e63x1/x2 /x3
Apfel/Tisch/
Pfennig
|
+
Butter/Uhr/
Nagel
|
+
Auto/Blume/
Kerze
|
+
Auto/Blume/
Kerze
|
-
|
-
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-
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IP (Intensive Protocol)
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EE
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MMSE
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|
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current year / season / date / day of the week /
month
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q1nmm1/2 /3 /4 /5
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-
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q3mm1/2 /3 /4 /5
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+
|
Z5E59a
add.: time
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z6e59/59a/57/60/58
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z7e59/59a/57/60/58
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|
short term memory (1.)
|
q1nmm61/62 /63
Apfel/Tisch/
Pfennig
|
-
|
q3mm61/62 /63
Apfel/Tisch/
Pfennig
|
+
Käse/Fahrrad/
Buch
|
z5e56x1/x2/x3
Schlüssel/Bürste/
Lampe
|
z6e56x1/x2/x3
Apfel/Tisch/Pfennig
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z7e56x1/x2/x3
Auto/Blume/Kerze
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|
currently in which state / town / part of town / district
/ story
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q1nmm7/8 /9 /10 /11
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-
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q3mm7/8 /9 /10 /11
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+
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Z5E56a1/2/3/4/5
state/"Bundesland"/town/district/story
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Z6E56a1/2/3/4/5
state/"Bundesland"/town/district/story
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Z7E56a1/2/3/4/5
state/"Bundesland"/town/district/story
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1./ 2. / 3. / 4. / 5. substraction
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q1nmm121/122 /123 /124 /125
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-
|
q3mm121/122 /123 /124 /125
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+
|
z5e61x1/x2/x3/x4/x5
|
z6e61x1/x2/x3/x4/x5
|
z7e61x1/x2/x3/x4/x5
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|
backwards spelling
(V / O / G / E / L)
|
q1nmm131/132 /133 /134 /135
|
-
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q3mm13
|
+
|
-
|
-
|
-
|
|
writing a complete sentence
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q1nmm14
|
-
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q3mm14
|
+
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Z5E62a1
|
Z6E62a1
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Z7E62a1
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|
figure drawing
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q1nmm15
|
-
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q3mm15
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+
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Z5E62a2
|
Z6E62a2
|
Z7E62a2
|
|
short term memory (2.)
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q1nmm161/162 /163
Apfel/Tisch/
Pfennig
|
-
|
q3mm161/162 /163
Apfel/Tisch/
Pfennig
|
+
Käse/Fahrrad/
Buch
|
Z5E63x1/x2/x3
Schlüssel/Bürste/
Lampe
|
Z6E63x1/x2/x3
Apfel/Tisch/Pfennig
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Z7E63x1/x2/x3
Auto/Blume/Kerze
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|
naming objects:
watch /pencil
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q1nmm171/172
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-
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q3mm171/172
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+
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Z5E64a1/2
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Z6E64a1/2
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Z7E64a1/2
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reading and explaining the sentence
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q1nmm18
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-
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q3mm18
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+
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Z5E64a3
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Z6E64a3
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Z7E64a3
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|
repeating a non-sense sentence
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q1nmm19
|
-
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q3mm19
|
+
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Z5E64a4
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Z6E64a4
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Z7E64a4
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|
taking a sheet of paper by right hand
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q1nmm201
|
-
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q3mm201
|
+
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Z5E64a5
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Z6E64a5
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Z7E64a5
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|
folding the sheet of paper
|
q1nmm202
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-
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q3mm202
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+
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Z5E64a6
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Z6E64a6
|
Z7E64a6
|
|
putting the sheet in the lap
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q1nmm203
|
-
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q3mm203
|
+
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Z5E64a7
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Z6E64a7
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Z7E64a7
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Enhanced Cued Recall
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|
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pointing
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q1nze1 to
q1nze16
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-
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+
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+
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Z5E77a2
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Z6E77a2
|
-
|
|
naming
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q1nbe1 to
q1nbe16
|
-
|
+
|
+
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Z5E77a3
|
Z6E77a3
|
-
|
|
immediate repeat
|
q1nuw1 to q1nuw16
|
-
|
+
|
+
|
Z5E77a4
|
Z6E77a4
|
-
|
|
1st free recall
|
q1n1fw1 to q1n1fw16
|
-
|
+
|
+
|
Z5E77a5
|
Z6E77a5
|
-
|
|
1st support
|
q1n1hi1 to q1n1hi16
|
-
|
+
|
+
|
Z5E77a6
|
Z6E77a6
|
-
|
|
2nd free recall
|
q1n2fw1 to q1n2fw16
|
-
|
+
|
+
|
Z5E77a7
|
Z6E77a7
|
-
|
|
2nd support
|
q1n2hi1 to q1n2hi16
|
-
|
+
|
+
|
Z5E77a8
|
Z6E77a8
|
-
|
|
3rd support
|
q1n3hi1 to q1n3hi16
|
-
|
-
|
-
|
-
|
-
|
-
|
|
1st recognition
|
q1n1we1 to q1n1we16
|
-
|
-
|
-
|
-
|
-
|
-
|
|
incidental learning
|
q1n1il1 to
q1n1il16
|
-
|
-
|
-
|
-
|
-
|
-
|
|
delayed free recall
|
q1nvfw1 to q1nvfw16
|
-
|
-
|
-
|
-
|
-
|
-
|
|
delayed support
|
q1nvhi1 to q1nvhi16
|
-
|
-
|
-
|
-
|
-
|
-
|
|
2nd recognition
|
q1n2we1 to q1n2we16
|
-
|
-
|
-
|
-
|
-
|
-
|
|
backwards calculating -2
|
q1nnrre2
|
-
|
q3nrre2
|
+
|
Z5E77a9
|
Z6E77a9
|
-
|
|
backwards calculating -3
|
q1nnrre3
|
-
|
q3nrre3
|
+
|
Z5E77a11
|
Z6E77a11
|
-
|
|
backwards calculating -7
|
q1nnrre7
|
-
|
-
|
-
|
-
|
-
|
-
|
|
backwards calculating -2 error
|
-
|
-
|
q3nnre2f
|
+
|
Z5E77a10
|
Z6E77a10
|
-
|
|
backwards calculating -3 error
|
-
|
-
|
q3nnre3f
|
+
|
Z5E77a12
|
Z6E77a12
|
-
|
|
Complex Figures
|
|
|
copy
|
q1n1ko1 to
q1n1ko18
|
-
|
-
|
-
|
-
|
-
|
-
|
|
reconstruction
|
q1n2ko1 to
q1n2ko18
|
-
|
-
|
-
|
-
|
-
|
-
|
|
Reitan Trail Making
|
|
|
test trial
|
q1ntraip
|
-
|
-
|
-
|
-
|
-
|
-
|
|
trailmaking
|
q1ntrait
|
-
|
-
|
-
|
-
|
-
|
-
|
|
Unusual Questions
|
|
|
How long is a 10 DM bill?
|
q1nugwf1
|
-
|
-
|
-
|
-
|
-
|
-
|
|
How much weighs a normal table phone?
|
q1nugwf2
|
-
|
-
|
-
|
-
|
-
|
-
|
|
How much on average is a new trumpet?
|
q1nugwf3
|
-
|
-
|
-
|
-
|
-
|
-
|
|
You get a kg of average envelopes; how many are they?
|
q1nugwf4
|
-
|
-
|
-
|
-
|
-
|
-
|
|
How quickly on average can a horse gallop?
|
q1nugwf5
|
-
|
-
|
-
|
-
|
-
|
-
|
|
How long is the spinal column of the average
human-being?
|
q1nugwf6
|
-
|
-
|
-
|
-
|
-
|
-
|
Dementia:
Raw Constructs Created in BASE
Note:
According to the design, EE construct names for Time 1
have the prefix k1, names for Time 2 have the prefix k2,
names for Times 3 have the prefix k3, names for Time 4 have the
prefix k4, and names for Time 5 have the prefix k5.
IP construct names for Time 1 have the prefix q1, names for
Time 3 have the prefix q3, and names for Time 4 have the prefix
q4.
Variables for Time 5, Time 6, and Time 7 have
been administered in the EE, but are displayed below according
to the task performed.
Variable names for Time 5 have the prefix z5 or q5, names for Time 6
have the prefix z6 or q6,
and names for Times 7 have the prefix q7.
|
Constructs
|
Construct names
Time 1
|
Construct names
Time 2
|
Construct names
Time 3
|
Construct names
Time 4
|
Construct names
Time 5
|
Construct names
Time 6
|
Construct names
Time 7
|
|
Short MMS
|
|
1.
|
k1zsmmco
|
+
|
+
|
+
|
+
|
-
|
-
|
|
sum score (weighted)
|
|
2.
|
k1z56ts
|
+
|
+
|
+
|
+
|
+
|
+
|
|
sum score
|
|
3.
|
k1z56sum
|
+
|
+
|
+
|
+
|
-
|
-
|
|
registration (Nachsprechleistung)
|
|
MMSE
|
|
1.
|
q1mmse30
|
-
|
+
|
+
|
-
|
+
|
+
|
|
sum score (items q1nmm1 to q1nmm203)
|
|
2.
|
q1mmsest
|
-
|
+
|
+
|
-
|
-
|
-
|
|
estimation of sum score
(if less equal 5 missings, the missing values were estimated
by the mean of the non-missings)
|
|
ECR
|
|
1.
|
q1ecr
|
-
|
-
|
-
|
-
|
+
|
-
|
|
Complex figures
|
|
1.
|
q1komfco
|
-
|
-
|
-
|
-
|
-
|
-
|
|
sum score (of items q1n1ko1 to q1n1ko18) / 2
|
|
2.
|
q1komfre
|
-
|
-
|
-
|
-
|
-
|
-
|
|
sum score (of items q1n2ko1 to q1n2ko18) / 2
|